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LIVING THE CONCERT OF LIFE
ALL GENETICS 2022

LET´S OWN MY TRAITS

WEIGHT MANAGEMENT GENES

It has been thoroughly documented that the percentage of the population that is overweight and obese is rising to epidemic proportions all over the world with all the attendant health, social and economic consequences.​

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It has long been suspected that "one size does not fit all" in terms of determining the optimal diet for an individual, and this has been demonstrated over the recent years in studies on gene-diet interactions and the emergence of nutrigenetics. The goal of nutrigenetics is to add a level of personalization to a prescribed diet, by adjusting it according to genetic variation. For example people carrying the MTHFR 677T allele require more folate and B vitamins in their diet in order to keep homocysteine levels low. Nutrigenetic testing in clinical practice analyzes genes principally involved in the metabolism and transport of nutrients, removal of toxins and protection from oxidation. According to the particular pattern of genetic variation, personalized advice can be generated that contains recommendations on dietary and lifestyle modifications to attain genetically based, specific goals in nutrition and exercise.

weight management

NUTRITION
GENES

Since the sequencing of the human gemone, there's been a lot of interest in nutrigenomics. It’s long been clear that we don’t all respond the same way to the same dietary interventions. Some people do really well on a higher fat diet. Others develop high triglycerides or cholesterol on the same diet. Some people lose more weight when they reduce carbs. Others lose more weight when they increase complex carbs and reduce fat.

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If these differences are genetic, we can skip some of the trial-and-error and zero in on the best approach for each unique individual based on their DNA.

nutrition

FITNESS
GENES

Two gene variants, ACE I/D and ACTN3 R577X, have been consistently associated with endurance (ACE I/I) and power-related (ACTN3 R/R) performance, though neither can be considered predictive. The role of genetic variation in injury risk and outcomes is more sparsely studied, but genetic testing for injury susceptibility could be beneficial in protecting young athletes from serious injury.

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Both the scientific and sporting communities acknowledge that genetic factors undoubtedly contribute to athletic performance. As of 2019, more than 400 genetic variants had been associated with physical performance, with more than 20 variants being associated with elite athlete status.

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A primary challenge when attempting to describe the influence of genetic factors on athletic performance is its multifactorial nature. Every sport has unique physical requirements and these requirements can be dramatically different between sports. Therefore, any study of the genetic influence on performance considers the performance components most appropriate for the sport of interest.

fitness

SKIN

GENES

Your skin reveals the story of your life, from the texture of your skin throughout your youth to the smile lines around your mouth and eyes resulting from laughter as you age. Your skin plays a significant role in your personality and makes you who you are today.

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Your skin is your largest organ, the first line of defense against all external factors, and often one of the first things people notice about you. But how to take the best care of your skin can be a confusing problem. There is no shortage of products with big promises about youthful skin, but the evidence for their effect isn't always clear. It's easy to spend hundreds of dollars on products that may not work well for you, even when they seem to benefit someone you know. So why not let your unique genetics help guide your choices?

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Your genetics predispose you to specific skin characteristics and understanding what role your genes have can help you choose the right skin care to counter the effects and prevent damage in the future.

skin

Epigenetic testing is the next generation in DNA testing. Testing your genes provides valuable insights into your potential pre-dispositions, but you still don't know how your environment has affected your gene expression until you look at epigenetics. For example, when you have a normal gene result, meaning you do not have a variant (a change in the DNA base pairs), research suggests you are at an average to decreased risk for that particular trait or disease. Only when you layer your methylation results on top of the DNA results do you get more in depth information about the gene’s abilities at that point in time.

 

Another way to think about this example is with MTHFR. MTHFR codes for an enzyme that is responsible for generating the final form of folate (5-MTHF) that the cells can use. Individuals with a variant in the MTHFR gene have been shown to have lower folate levels. The MTHFR gene is also under methylation control. If the gene is undermethylated, then the gene can still send instructions to make more enzymes. If the gene is over-methylated, then the gene will be silenced and will be unable to send the necessary instructions for the enzyme.

health

HEALTH

GENES

MY NEWBORN
GENES

This test was developed by a team of important clinical and molecular geneticists, pediatricians and scientists with experience in pediatric genetic conditions. This test was carefully designed to provide accurate and useful results, based on years of research and clinical experience in molecular diagnosis. Our test met strict criteria, including:

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  • Analytical validity, or how accurately a test can detect a certain genetic change (or variant). All DNA samples for the newborn test are analyzed in our CLIA-certified laboratory using advanced DNA sequencing technology that is> 95% accurate.

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  • Clinical validity, or how well a genetic test can predict a certain disease. Our test only detects highly penetrating genetic changes. This means that if someone is born with genetic changes evaluated by this test, there is a high probability (> 80%) of developing symptoms of the associated disease.

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  • Clinical utility, or if a genetic test provides useful information that can help improve treatment options or other health care decisions. Our test only detects conditions that can be treated * with medications, diet modification or other therapies.

newborn

The objective of DIPTALENT is to help parents identify their child’s natural talents and aptitudes that may not be obvious at a young age. Giving your child a head start in proper nurture can maximize those aptitudes to the fullest potential.

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DIPTALENT covers 46 talents and traits. The test reports come with a Career Profiling assessed by our team of psychologists based on one’s unique abilities detected from his/her genetic makeup. This profile can provide an individual with good educational and career guidance. Expert Suggestions giving insightful details to help parents effectively nurture and develop their child’s character and talents are also included in the report. 

MY KIDS
GENES

Kids Genetics

FERTILITY
GENES

Nearly 50 million couples worldwide experience infertility. Although the causes of infertility are often complicated and difficult to identify, health and lifestyle factors affect the ability of both men and women to reproduce. In women, older age, inability to produce ova (mature oocytes), and presence of endometriosis or polycystic ovarian syndrome (PCOS) can play a large role in infertility. Among men, sperm count and quality are variable and play an important role in successful fertilization. For both sexes, factors known to affect fertility include the viability of gametes (in women, oocytes, and in men, sperm), hormonal imbalances, presence of sexually transmitted infections (STI’s), substance use, over- or under-weight, and past or present chronic disease. Clearly, many contributing factors must align for healthy fertilization and pregnancy to occur. One of these factors is nutrition. There is mounting evidence to support the relationship between various dietary components and fertility, but the effects of nutritional interventions on fertility remain unclear because of variations in response to those interventions across individuals.

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Your best diet for optimal fertility depends on the specific variants you have for these nutrient-related genes. Understanding your genetic profile and its implications on your unique response to the foods, supplements and beverages you consume will provide you with the tools needed to make the best dietary choices.

Fertility Genetics

GO 360

Our microbiome and biological aging (how you’re aging internally), and cellular function health play a significant role in our health.

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Trillions of bacteria directly influence our digestive system. The analysis of genes that express microbes allows us to identify which metabolites produce. This helps determine your role in your body's ecosystem. But all that is not useful if they are only data. When we understand metabolites, we can also understand how to affect them with food, lifestyle and supplements to change intestinal bacteria.

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On the other hand, the DIP-360 test reveals how a your biological aging is being shaped by lifestyle and environment over time, which makes it an updated health test that you can repeat! Epigenetic information decides which genes are turned ‘on’ or ‘off’, which ultimately affects the risk of developing chronic illnesses (such as different types of cancer, type 2 diabetes, cardiovascular disease or neurodegenerative pathologies).

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By measuring how specific interventions (for instance changes in diet, exercise or sleep) are affecting the molecular health of your cells, you can change their future for the better.

DIP-360

HOW IT WORKS

how it work
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Mail Sample

View Results

We believe that you should always maintain control over your genetic information, which is why there’s no middleman or specialist between you and your profile. We deliver your DNA test results directly to you as soon as they become available, on your phone or computer.

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Your test results aren’t just a list of your gene variants. You’ll also get insights and tips, so that you can make choices that may be right for you. And while your profile will let you know if you’re predisposed to certain traits, it’s not a diagnosis, so interpret your results with care.

SAMPLE COLLECTION INSTRUCTIONS

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Collection precautions
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  • Do NOT eat, drink, smoke or chew gum for 30 minutes before giving your saliva sample.

  • Do NOT remove the plastic film from the funnel lid.

 

Procedure: Most people take between 2 and 5 minutes to deliver a saliva sample following steps 1 to 5.

1

Spit into funnel until the amount of liquid saliva (not bubbles) reaches the fill line shown in picture #1.

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2

Hold the tube upright with one hand. Close the funnel lid with the other hand (as shown) by firmly pushing the lid until you hear a loud click. The liquid in the lid will be released into the tube to mix with the saliva. Make sure that the lid is closed tightly.

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3

Hold the tube upright. Unscrew the funnel from the tube.

4

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Use the small cap to close the tube tightly.

5

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Shake the capped tube for 5 seconds. Discard or recycle the funnel.

Additional notes
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Intended use: For the collection of human DNA from saliva samples.

Contents: Kit contains stabilizing liquid.

Warnings and precautions: Wash with water if stabilizing liquid comes in contact with eyes or skin. Do NOT ingest.

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Small cap may pose a choking hazard.

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Storage: 15°C–30°C

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